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4TKP

Complex of Ubc13 with the RING domain of the TRIM5alpha retroviral restriction factor

Summary for 4TKP
Entry DOI10.2210/pdb4tkp/pdb
DescriptorUbiquitin-conjugating enzyme E2 N, Tripartite motif-containing protein 5, SULFATE ION, ... (5 entities in total)
Functional Keywordshiv restriction, trim5, ubc13, e3 ubiquitin ligase, ring dimerization, ligase
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight27773.56
Authors
Johnson, R.,Taylor, A.B.,Hart, P.J.,Ivanov, D.N. (deposition date: 2014-05-27, release date: 2015-07-22, Last modification date: 2023-12-27)
Primary citationYudina, Z.,Roa, A.,Johnson, R.,Biris, N.,de Souza Aranha Vieira, D.A.,Tsiperson, V.,Reszka, N.,Taylor, A.B.,Hart, P.J.,Demeler, B.,Diaz-Griffero, F.,Ivanov, D.N.
RING Dimerization Links Higher-Order Assembly of TRIM5 alpha to Synthesis of K63-Linked Polyubiquitin.
Cell Rep, 12:788-797, 2015
Cited by
PubMed: 26212332
DOI: 10.1016/j.celrep.2015.06.072
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.08 Å)
Structure validation

217705

数据于2024-03-27公开中

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