4TKM

Crystal structure of NADH-dependent reductase A1-R' complexed with NAD

Summary for 4TKM

• Entry DOI: 10.2210/pdb4tkm/pdb
• Related: 4TKL
• Descriptor: NADH-dependent reductase for 4-deoxy-L-erythro-5-hexoseulose uronate, SULFATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total)
• Functional Keywords: alpha/beta/alpha, rossmann-fold, alginate metabolism, short-chain dehydrogenase/reductase, oxidoreductase
• Biological source: Sphingomonas sp. A1
• Total number of polymer chains: 2
• Total formula weight: 55881.90

Authors

Takase, R.,Mikami, B.,Kawai, S.,Murata, K.,Hashimoto, W. (deposition date: 2014-05-27, release date: 2014-06-25, Last modification date: 2023-11-08)

• Primary citation: Takase, R.,Mikami, B.,Kawai, S.,Murata, K.,Hashimoto, W.; Structure-based Conversion of the Coenzyme Requirement of a Short-chain Dehydrogenase/Reductase Involved in Bacterial Alginate Metabolism.; J.Biol.Chem., 289:33198-33214, 2014; PubMed: 25288804; DOI: 10.1074/jbc.M114.585661

Experimental method

X-RAY DIFFRACTION (2.67 Å)