4S2O

OXA-10 in complex with Avibactam

Summary for 4S2O

• Entry DOI: 10.2210/pdb4s2o/pdb
• Descriptor: Beta-lactamase OXA-10, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, COBALT (II) ION, ... (4 entities in total)
• Functional Keywords: hydrolase-antibiotic complex, hydrolase/antibiotic
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 2
• Total formula weight: 55818.83

Authors

King, D.T.,Strynadka, N.C.J. (deposition date: 2015-01-21, release date: 2015-02-25, Last modification date: 2017-11-22)

• Primary citation: King, D.T.,King, A.M.,Lal, S.M.,Wright, G.D.,Strynadka, N.C.; Molecular Mechanism of Avibactam-Mediated beta-Lactamase Inhibition.; ACS Infect Dis, 1:175-184, 2015; PubMed: 27622530; DOI: 10.1021/acsinfecdis.5b00007

Experimental method

X-RAY DIFFRACTION (1.7 Å)