4S2N

OXA-48 in complex with Avibactam at pH 8.5

Summary for 4S2N

• Entry DOI: 10.2210/pdb4s2n/pdb
• Descriptor: Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, ... (4 entities in total)
• Functional Keywords: hydrolase-antibiotic complex, hydrolase/antibiotic
• Biological source: Klebsiella pneumoniae; More
• Total number of polymer chains: 4
• Total formula weight: 122741.93

Authors

King, D.T.,Strynadka, N.C.J. (deposition date: 2015-01-21, release date: 2015-02-25, Last modification date: 2023-12-06)

• Primary citation: King, D.T.,King, A.M.,Lal, S.M.,Wright, G.D.,Strynadka, N.C.; Molecular Mechanism of Avibactam-Mediated beta-Lactamase Inhibition.; ACS Infect Dis, 1:175-184, 2015; PubMed: 27622530; DOI: 10.1021/acsinfecdis.5b00007

Experimental method

X-RAY DIFFRACTION (2 Å)