4S2E

Phosphate ion bound Crystal structure of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5

Summary for 4S2E

• Entry DOI: 10.2210/pdb4s2e/pdb
• Related: 2PBR
• Descriptor: Thymidylate kinase, PHOSPHATE ION (3 entities in total)
• Functional Keywords: transferase, atp binding, tmp binding
• Biological source: Aquifex aeolicus
• Total number of polymer chains: 2
• Total formula weight: 44995.86

Authors

Biswas, A.,Jeyakanthan, J.,Sekar, K. (deposition date: 2015-01-20, release date: 2016-01-20, Last modification date: 2023-09-20)

• Primary citation: Biswas, A.,Shukla, A.,Chaudhary, S.K.,Santhosh, R.,Jeyakanthan, J.,Sekar, K.; Structural studies of a hyperthermophilic thymidylate kinase enzyme reveal conformational substates along the reaction coordinate.; Febs J., 284:2527-2544, 2017; PubMed: 28627020; DOI: 10.1111/febs.14140

Experimental method

X-RAY DIFFRACTION (2.35 Å)