4S1B
Crystal Structure of L. monocytogenes phosphodiesterase PgpH HD domain in complex with Cyclic-di-AMP
Summary for 4S1B
Entry DOI | 10.2210/pdb4s1b/pdb |
Related | 4S1C |
Descriptor | Lmo1466 protein, FE (III) ION, (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ... (4 entities in total) |
Functional Keywords | c-di-amp, listeria monocytogenes, phosphodiesterase, hd domain, hydrolase |
Biological source | Listeria monocytogenes |
Total number of polymer chains | 2 |
Total formula weight | 51785.81 |
Authors | |
Primary citation | Huynh, T.N.,Luo, S.,Pensinger, D.,Sauer, J.D.,Tong, L.,Woodward, J.J. An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence. Proc.Natl.Acad.Sci.USA, 112:E747-E756, 2015 Cited by PubMed: 25583510DOI: 10.1073/pnas.1416485112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.099 Å) |
Structure validation
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