4RZE
Crystal Structure Analysis of the NUR77 Ligand Binding Domain, L437W,D594E mutant
Summary for 4RZE
| Entry DOI | 10.2210/pdb4rze/pdb |
| Related | 4RZF 4RZG |
| Descriptor | Nuclear receptor subfamily 4 group A member 1, GLYCEROL (3 entities in total) |
| Functional Keywords | transcription |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P22736 |
| Total number of polymer chains | 2 |
| Total formula weight | 57678.66 |
| Authors | Fengwei, L.,Xuyang, T.,Anzhong, L.,Li, L.,Yuan, L.,Hangzi, C.,Qiao, W.,Tianwei, L. (deposition date: 2014-12-21, release date: 2015-03-18, Last modification date: 2024-02-28) |
| Primary citation | Li, L.,Liu, Y.,Chen, H.Z.,Li, F.W.,Wu, J.F.,Zhang, H.K.,He, J.P.,Xing, Y.Z.,Chen, Y.,Wang, W.J.,Tian, X.Y.,Li, A.Z.,Zhang, Q.,Huang, P.Q.,Han, J.,Lin, T.,Wu, Q. Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation. Nat.Chem.Biol., 11:339-346, 2015 Cited by PubMed: 25822914DOI: 10.1038/nchembio.1788 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.49 Å) |
Structure validation
Download full validation report
