4RSM

Crystal structure of carbohydrate transporter msmeg_3599 from mycobacterium smegmatis str. mc2 155, target efi-510970, in complex with d-threitol

Summary for 4RSM

Entry DOI	10.2210/pdb4rsm/pdb
Descriptor	Periplasmic binding protein/LacI transcriptional regulator, D-Threitol (3 entities in total)
Functional Keywords	sugar transporter, abc-type, enzyme function initiative, efi, structural genomics, transport protein, hydrolase
Biological source	Mycobacterium smegmatis
Cellular location	Cell membrane ; Lipid-anchor : A0QYB5
Total number of polymer chains	4
Total formula weight	137874.78
Authors	Patskovsky, Y.,Toro, R.,Bhosle, R.,Al Obaidi, N.,Morisco, L.L.,Wasserman, S.R.,Chamala, S.,Attonito, J.D.,Scott Glenn, A.,Chowdhury, S.,Lafleur, J.,Hillerich, B.,Siedel, R.D.,Love, J.,Whalen, K.L.,Gerlt, J.A.,Almo, S.C.,Enzyme Function Initiative (EFI) (deposition date: 2014-11-08, release date: 2014-12-10, Last modification date: 2024-02-28)
Primary citation	Huang, H.,Carter, M.S.,Vetting, M.W.,Al-Obaidi, N.,Patskovsky, Y.,Almo, S.C.,Gerlt, J.A. A General Strategy for the Discovery of Metabolic Pathways: d-Threitol, l-Threitol, and Erythritol Utilization in Mycobacterium smegmatis. J.Am.Chem.Soc., 137:14570-14573, 2015 Cited by PubMed: 26560079 DOI: 10.1021/jacs.5b08968 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation