4RS1

Crystal structure of receptor-cytokine complex

Summary for 4RS1

Entry DOI	10.2210/pdb4rs1/pdb
Descriptor	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha, Granulocyte-macrophage colony-stimulating factor, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	cytokine, receptor, cytokine receptor-cytokine complex, cytokine receptor/cytokine
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	46278.27
Authors	Broughton, S.E.,Parker, M.W.,Dhagat, U. (deposition date: 2014-11-06, release date: 2015-11-11, Last modification date: 2020-07-29)
Primary citation	Broughton, S.E.,Hercus, T.R.,Nero, T.L.,Dottore, M.,McClure, B.J.,Dhagat, U.,Taing, H.,Gorman, M.A.,King-Scott, J.,Lopez, A.F.,Parker, M.W. Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling. Structure, 24:1271-1281, 2016 Cited by PubMed: 27396825 DOI: 10.1016/j.str.2016.05.017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.68 Å)

Structure validation