4RRY
Crystal Structure of Apo Murine H90W Cyclooxygenase-2
Summary for 4RRY
Entry DOI | 10.2210/pdb4rry/pdb |
Related | 4RRW 4RRX 4RRZ 4RS0 |
Descriptor | Prostaglandin G/H synthase 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | prostaglandin-endoperoxide synthase, glycosylation, membrane, oxidoreductase |
Biological source | Mus musculus (mouse) |
Total number of polymer chains | 4 |
Total formula weight | 274744.57 |
Authors | Xu, S.,Blobaum, A.L.,Banerjee, S.,Marnett, L.J. (deposition date: 2014-11-06, release date: 2015-04-08, Last modification date: 2023-09-20) |
Primary citation | Blobaum, A.L.,Xu, S.,Rowlinson, S.W.,Duggan, K.C.,Banerjee, S.,Kudalkar, S.N.,Birmingham, W.R.,Ghebreselasie, K.,Marnett, L.J. Action at a Distance: MUTATIONS OF PERIPHERAL RESIDUES TRANSFORM RAPID REVERSIBLE INHIBITORS TO SLOW, TIGHT BINDERS OF CYCLOOXYGENASE-2. J.Biol.Chem., 290:12793-12803, 2015 Cited by PubMed: 25825493DOI: 10.1074/jbc.M114.635987 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.429 Å) |
Structure validation
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