4RKX
Identification and characterization of a small molecule inhibitor of S. pyogenes SpeB.
Summary for 4RKX
Entry DOI | 10.2210/pdb4rkx/pdb |
Related | 4d8b 4D8e 4d8i |
Descriptor | Streptopain, NITRATE ION, benzyl (cyanomethyl)carbamate, ... (4 entities in total) |
Functional Keywords | papain fold, cysteine protease, secreted, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Streptococcus pyogenes |
Total number of polymer chains | 1 |
Total formula weight | 28933.90 |
Authors | Wang, A.Y.,Gonzalez-Paez, G.E.,Wolan, D.W. (deposition date: 2014-10-14, release date: 2015-07-22, Last modification date: 2023-09-20) |
Primary citation | Wang, A.Y.,Gonzalez-Paez, G.E.,Wolan, D.W. Identification and Co-complex Structure of a New S. pyogenes SpeB Small Molecule Inhibitor. Biochemistry, 54:4365-4373, 2015 Cited by PubMed: 26132413DOI: 10.1021/acs.biochem.5b00607 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
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