4RKK

Structure of a product bound phosphatase

4RKK の概要

• エントリーDOI: 10.2210/pdb4rkk/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900009 PRD_900010 PRD_900035
• 分子名称: Laforin, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: dual specificity phosphatase, carbohydrate binding module, phosphatase, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 79733.25

構造登録者

Vander Kooi, C.W. (登録日: 2014-10-13, 公開日: 2015-01-07, 最終更新日: 2024-02-28)

• 主引用文献: Raththagala, M.,Brewer, M.K.,Parker, M.W.,Sherwood, A.R.,Wong, B.K.,Hsu, S.,Bridges, T.M.,Paasch, B.C.,Hellman, L.M.,Husodo, S.,Meekins, D.A.,Taylor, A.O.,Turner, B.D.,Auger, K.D.,Dukhande, V.V.,Chakravarthy, S.,Sanz, P.,Woods, V.L.,Li, S.,Vander Kooi, C.W.,Gentry, M.S.; Structural mechanism of laforin function in glycogen dephosphorylation and lafora disease.; Mol.Cell, 57:261-272, 2015; PubMed: 25544560; DOI: 10.1016/j.molcel.2014.11.020

実験手法

X-RAY DIFFRACTION (2.4 Å)