4RHW

Crystal structure of Apaf-1 CARD and caspase-9 CARD complex

Summary for 4RHW

• Entry DOI: 10.2210/pdb4rhw/pdb
• Descriptor: Apoptotic protease-activating factor 1, Caspase-9, SULFATE ION, ... (5 entities in total)
• Functional Keywords: death domain superfamily, apoptosis
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 70625.29

Authors

Hu, Q.,Wu, D.,Yan, C.,Shi, Y. (deposition date: 2014-10-03, release date: 2014-10-15, Last modification date: 2023-11-08)

• Primary citation: Hu, Q.,Wu, D.,Chen, W.,Yan, Z.,Yan, C.,He, T.,Liang, Q.,Shi, Y.; Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome.; Proc. Natl. Acad. Sci. U.S.A., 111:16254-16261, 2014; PubMed: 25313070; DOI: 10.1073/pnas.1418000111

Experimental method

X-RAY DIFFRACTION (2.1 Å)