4RH1

Spore photoproduct lyase C140A/S76C mutant with bound AdoMet and dinucleoside spore photoproduct

Summary for 4RH1

• Entry DOI: 10.2210/pdb4rh1/pdb
• Related: 4RH0
• Descriptor: Spore photoproduct lyase, IRON/SULFUR CLUSTER, [(3S)-3-amino-4-hydroxy-4-oxo-butyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl]-methyl-selanium, ... (6 entities in total)
• Functional Keywords: radical adomet enzyme, radical sam enzyme, dna repair, tim barrel, dna lyase, lyase
• Biological source: Geobacillus thermodenitrificans NG80-2
• Total number of polymer chains: 1
• Total formula weight: 44818.72

Authors

Benjdia, A.,Heil, K.,Winkler, A.,Carell, T.,Schlichting, I. (deposition date: 2014-10-01, release date: 2014-10-22, Last modification date: 2024-02-28)

• Primary citation: Benjdia, A.,Heil, K.,Winkler, A.,Carell, T.,Schlichting, I.; Rescuing DNA repair activity by rewiring the H-atom transfer pathway in the radical SAM enzyme, spore photoproduct lyase.; Chem.Commun.(Camb.), 50:14201-14204, 2014; PubMed: 25285338; DOI: 10.1039/c4cc05158k

Experimental method

X-RAY DIFFRACTION (2.6 Å)