4RH1

Spore photoproduct lyase C140A/S76C mutant with bound AdoMet and dinucleoside spore photoproduct

4RH1 の概要

• エントリーDOI: 10.2210/pdb4rh1/pdb
• 関連するPDBエントリー: 4RH0
• 分子名称: Spore photoproduct lyase, IRON/SULFUR CLUSTER, [(3S)-3-amino-4-hydroxy-4-oxo-butyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl]-methyl-selanium, ... (6 entities in total)
• 機能のキーワード: radical adomet enzyme, radical sam enzyme, dna repair, tim barrel, dna lyase, lyase
• 由来する生物種: Geobacillus thermodenitrificans NG80-2
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 44818.72

構造登録者

Benjdia, A.,Heil, K.,Winkler, A.,Carell, T.,Schlichting, I. (登録日: 2014-10-01, 公開日: 2014-10-22, 最終更新日: 2024-02-28)

• 主引用文献: Benjdia, A.,Heil, K.,Winkler, A.,Carell, T.,Schlichting, I.; Rescuing DNA repair activity by rewiring the H-atom transfer pathway in the radical SAM enzyme, spore photoproduct lyase.; Chem.Commun.(Camb.), 50:14201-14204, 2014; PubMed: 25285338; DOI: 10.1039/c4cc05158k

実験手法

X-RAY DIFFRACTION (2.6 Å)