4REW
Crystal structure of the non-phosphorylated human alpha1 beta2 gamma1 holo-AMPK complex
Summary for 4REW
Entry DOI | 10.2210/pdb4rew/pdb |
Related | 4RED 4RER |
Descriptor | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... (5 entities in total) |
Functional Keywords | human alpha1 beta2 gamma1 holo-ampk complex, serine/threonine protein kinase, axin, camkkbeta, lkb1, glycogen, phosphorylation, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm : Q13131 |
Total number of polymer chains | 3 |
Total formula weight | 120008.98 |
Authors | Zhou, X.E.,Ke, J.,Li, X.,Wang, L.,Gu, X.,de Waal, P.W.,Tan, M.H.E.,Wang, D.,Wu, D.,Xu, H.E.,Melcher, K. (deposition date: 2014-09-24, release date: 2014-12-10, Last modification date: 2023-09-20) |
Primary citation | Li, X.,Wang, L.,Zhou, X.E.,Ke, J.,de Waal, P.W.,Gu, X.,Tan, M.H.,Wang, D.,Wu, D.,Xu, H.E.,Melcher, K. Structural basis of AMPK regulation by adenine nucleotides and glycogen. Cell Res., 25:50-66, 2015 Cited by PubMed: 25412657DOI: 10.1038/cr.2014.150 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.58 Å) |
Structure validation
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