4RE1
Crystal structure of human TEAD1 and disulfide-engineered YAP
Summary for 4RE1
Entry DOI | 10.2210/pdb4re1/pdb |
Descriptor | Transcriptional enhancer factor TEF-1, Yorkie homolog, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | immunoglobulin-like fold, transcription regulation, dna-binding, protein-protein interaction, phosphoprotein, nucleus, transcription-protein binding complex, transcription/protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P28347 Cytoplasm: P46937 |
Total number of polymer chains | 4 |
Total formula weight | 83009.26 |
Authors | |
Primary citation | Zhou, Z.,Hu, T.,Xu, Z.,Lin, Z.,Zhang, Z.,Feng, T.,Zhu, L.,Rong, Y.,Shen, H.,Luk, J.M.,Zhang, X.,Qin, N. Targeting Hippo pathway by specific interruption of YAP-TEAD interaction using cyclic YAP-like peptides. Faseb J., 29:724-732, 2015 Cited by PubMed: 25384421DOI: 10.1096/fj.14-262980 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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