4RBX
Crystal structure of human alpha-defensin 5, HD5 (Glu21Arg mutant)
Summary for 4RBX
Entry DOI | 10.2210/pdb4rbx/pdb |
Related | 1ZMP 4E82 4E83 4E86 4RBW |
Descriptor | Defensin-5, SULFATE ION (3 entities in total) |
Functional Keywords | mutant e21r-hd5, beta-sheet, antimicrobial peptide, paneth cells defensin, human alpha-defensin, antimicrobial protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted : Q01523 |
Total number of polymer chains | 1 |
Total formula weight | 3910.50 |
Authors | Pazgier, M.,Gohain, N.,Tolbert, W.D. (deposition date: 2014-09-13, release date: 2015-07-29, Last modification date: 2023-09-20) |
Primary citation | Wang, C.,Shen, M.,Gohain, N.,Tolbert, W.D.,Chen, F.,Zhang, N.,Yang, K.,Wang, A.,Su, Y.,Cheng, T.,Zhao, J.,Pazgier, M.,Wang, J. Design of a potent antibiotic peptide based on the active region of human defensin 5. J.Med.Chem., 58:3083-3093, 2015 Cited by PubMed: 25782105DOI: 10.1021/jm501824a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.1 Å) |
Structure validation
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