4R8Z

Crystal Structure of PA4781 HD-GYP domain from Pseudomonas aeruginosa at 2.2A resolution showing a bi-metallic Ni ion center

Summary for 4R8Z

Entry DOI	10.2210/pdb4r8z/pdb
Descriptor	Cyclic di-GMP phosphodiesterase, NICKEL (II) ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	bimetallic, c-di-gmp, pde, phosphdiesterase, cyclic-di-gmp, biofilm, hydrolase
Biological source	Pseudomonas aeruginosa PAO1
Total number of polymer chains	2
Total formula weight	48321.89
Authors	Giardina, G.,Cutruzzolaa, F.,Rinaldo, S.,Stelitano, V. (deposition date: 2014-09-03, release date: 2015-03-04, Last modification date: 2024-02-28)
Primary citation	Rinaldo, S.,Paiardini, A.,Stelitano, V.,Brunotti, P.,Cervoni, L.,Fernicola, S.,Protano, C.,Vitali, M.,Cutruzzola, F.,Giardina, G. Structural basis of functional diversification of the HD-GYP domain revealed by the Pseudomonas aeruginosa PA4781 protein, which displays an unselective bimetallic binding site. J.Bacteriol., 197:1525-1535, 2015 Cited by PubMed: 25691523 DOI: 10.1128/JB.02606-14 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation