4R8C
Crystal Structure of CNG mimicking NaK-ETPP mutant in complex with Rb+
Summary for 4R8C
Entry DOI | 10.2210/pdb4r8c/pdb |
Related | 3K0D 3K0G 4R50 4R6Z 4R7C 4R8B 4RAI 4RAR |
Descriptor | Potassium channel protein, RUBIDIUM ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total) |
Functional Keywords | alpha helical membrane protein, chimera channel, transport protein |
Biological source | Bacillus cereus ATCC 14579 |
Total number of polymer chains | 2 |
Total formula weight | 22752.94 |
Authors | De March, M.,Napolitano, L.M.R.,Onesti, S. (deposition date: 2014-09-01, release date: 2015-07-01, Last modification date: 2023-09-20) |
Primary citation | Napolitano, L.M.,Bisha, I.,De March, M.,Marchesi, A.,Arcangeletti, M.,Demitri, N.,Mazzolini, M.,Rodriguez, A.,Magistrato, A.,Onesti, S.,Laio, A.,Torre, V. A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels. Proc.Natl.Acad.Sci.USA, 112:E3619-E3628, 2015 Cited by PubMed: 26100907DOI: 10.1073/pnas.1503334112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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