4R7U
Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Vibrio cholerae in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin
Summary for 4R7U
Entry DOI | 10.2210/pdb4r7u/pdb |
Descriptor | UDP-N-acetylglucosamine 1-carboxyvinyltransferase, TETRAETHYLENE GLYCOL, [(1R)-1-hydroxypropyl]phosphonic acid, ... (6 entities in total) |
Functional Keywords | mura, fosfomycin, peptidoglycan, amino sugar and nucleotide sugar metabolism, peptidoglycan biosynthesis, structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, udp-n-acetylglucosamine 1-carboxyvinyltransferase, transferase-antibiotic complex, transferase/antibiotic |
Biological source | Vibrio cholerae O1 biovar El Tor str. N16961 |
Cellular location | Cytoplasm : Q9KP62 |
Total number of polymer chains | 4 |
Total formula weight | 183345.22 |
Authors | Nocek, B.,Maltseva, N.,Anderson, W.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-08-28, release date: 2014-09-24, Last modification date: 2017-11-22) |
Primary citation | Nocek, B.,Maltseva, N.,Anderson, W.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Vibrio cholerae in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin To be Published, |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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