4R0X

Allosteric coupling of conformational transitions in the FK1 domain of FKBP51 near the site of steroid receptor interaction

4R0X の概要

分子名称Peptidyl-prolyl cis-trans isomerase FKBP5 (2 entities in total)
機能のキーワードfk-506 binding domain, hsp90 cochaperone, immunophiline, peptidyl-prolyl isomerase, isomerase
由来する生物種Homo sapiens (human)
細胞内の位置Cytoplasm Q13451
ポリマー鎖数1
分子量合計13487.48
構造登録者
LeMaster, D.M.,Mustafi, S.M.,Brecher, M.,Zhang, J.,Heroux, A.,Li, H.M.,Hernandez, G. (登録日: 2014-08-02, 公開日: 2015-05-13, 最終更新日: 2015-07-22)
主引用文献
LeMaster, D.M.,Mustafi, S.M.,Brecher, M.,Zhang, J.,Heroux, A.,Li, H.,Hernandez, G.
Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins.
J.Biol.Chem., 290:15746-15757, 2015
PubMed: 25953903 (主引用文献が同じPDBエントリー)
DOI: 10.1074/jbc.M115.650655
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (1.2 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.1672004.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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