4R0X

Allosteric coupling of conformational transitions in the FK1 domain of FKBP51 near the site of steroid receptor interaction

4R0X の概要

• エントリーDOI: 10.2210/pdb4r0x/pdb
• 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP5 (2 entities in total)
• 機能のキーワード: fk-506 binding domain, hsp90 cochaperone, immunophiline, peptidyl-prolyl isomerase, isomerase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: Q13451
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 13487.48

構造登録者

LeMaster, D.M.,Mustafi, S.M.,Brecher, M.,Zhang, J.,Heroux, A.,Li, H.M.,Hernandez, G. (登録日: 2014-08-02, 公開日: 2015-05-13, 最終更新日: 2023-09-20)

• 主引用文献: LeMaster, D.M.,Mustafi, S.M.,Brecher, M.,Zhang, J.,Heroux, A.,Li, H.,Hernandez, G.; Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins.; J.Biol.Chem., 290:15746-15757, 2015; PubMed: 25953903; DOI: 10.1074/jbc.M115.650655

実験手法

X-RAY DIFFRACTION (1.2 Å)