4R05

Crystal structure of the refolded DENV3 methyltransferase

Summary for 4R05

• Entry DOI: 10.2210/pdb4r05/pdb
• Descriptor: Nonstructural protein NS5 (2 entities in total)
• Functional Keywords: methyltransferase, flavivirus, transferase
• Biological source: Dengue virus 3
• Total number of polymer chains: 2
• Total formula weight: 60139.17

Authors

Brecher, M.B.,Li, Z.,Zhang, J.,Chen, H.,Lin, Q.,Liu, B.,Li, H.M. (deposition date: 2014-07-29, release date: 2014-11-12, Last modification date: 2023-09-20)

• Primary citation: Brecher, M.B.,Li, Z.,Zhang, J.,Chen, H.,Lin, Q.,Liu, B.,Li, H.; Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase.; Protein Sci., 24:117-128, 2015; PubMed: 25352331; DOI: 10.1002/pro.2594

Experimental method

X-RAY DIFFRACTION (2.1 Å)