Summary for 5DZL
Entry DOI | 10.2210/pdb5dzl/pdb |
Related | 4QXW |
Descriptor | Carcinoembryonic antigen-related cell adhesion molecule 1 (1 entity in total) |
Functional Keywords | cell adhesion |
Biological source | Homo sapiens (Human) |
Cellular location | Isoform 1: Cell membrane ; Single-pass type I membrane protein . Isoform 2: Secreted . Isoform 3: Secreted . Isoform 4: Secreted . Isoform 5: Cell membrane; Single-pass type I membrane protein. Isoform 6: Cell membrane; Single-pass type I membrane protein. Isoform 7: Cell membrane; Single-pass type I membrane protein. Isoform 8: Cell membrane ; Single-pass type I membrane protein . Cell projection, microvillus membrane ; Single-pass type I membrane protein : P13688 |
Total number of polymer chains | 4 |
Total formula weight | 47945.00 |
Authors | Huang, Y.H.,Russell, A.,Gandhi, A.K.,Kondo, Y.,Chen, Q.,Petsko, G.A.,Blumberg, R.S. (deposition date: 2015-09-25, release date: 2015-10-07, Last modification date: 2023-09-27) |
Primary citation | Huang, Y.H.,Zhu, C.,Kondo, Y.,Anderson, A.C.,Gandhi, A.,Russell, A.,Dougan, S.K.,Petersen, B.S.,Melum, E.,Pertel, T.,Clayton, K.L.,Raab, M.,Chen, Q.,Beauchemin, N.,Yazaki, P.J.,Pyzik, M.,Ostrowski, M.A.,Glickman, J.N.,Rudd, C.E.,Ploegh, H.L.,Franke, A.,Petsko, G.A.,Kuchroo, V.K.,Blumberg, R.S. CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature, 517:386-390, 2015 Cited by PubMed: 25363763DOI: 10.1038/nature13848 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4006 Å) |
Structure validation
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