4QXV
CRYSTAL STRUCTURE of HUMAN TRANSTHYRETIN IN COMPLEX WITH LUTEOLIN AT 1.1 A RESOLUTION
Summary for 4QXV
Entry DOI | 10.2210/pdb4qxv/pdb |
Related | 1F41 1G1O 1SOK 1ZD6 |
Descriptor | Transthyretin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, GLYCEROL, ... (5 entities in total) |
Functional Keywords | beta barrel, wild type ttr, transthyretin, transport protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 28426.46 |
Authors | Begum, A.,Olofsson, A.,Sauer-Eriksson, A.E. (deposition date: 2014-07-22, release date: 2015-06-03, Last modification date: 2023-09-20) |
Primary citation | Iakovleva, I.,Begum, A.,Pokrzywa, M.,Walfridsson, M.,Sauer-Eriksson, A.E.,Olofsson, A. The flavonoid luteolin, but not luteolin-7-o-glucoside, prevents a transthyretin mediated toxic response. Plos One, 10:e0128222-e0128222, 2015 Cited by PubMed: 26020516DOI: 10.1371/journal.pone.0128222 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.12 Å) |
Structure validation
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