Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005179 | molecular_function | hormone activity |
A | 0005515 | molecular_function | protein binding |
A | 0005576 | cellular_component | extracellular region |
A | 0005615 | cellular_component | extracellular space |
A | 0005737 | cellular_component | cytoplasm |
A | 0006144 | biological_process | purine nucleobase metabolic process |
A | 0007165 | biological_process | signal transduction |
A | 0035578 | cellular_component | azurophil granule lumen |
A | 0042802 | molecular_function | identical protein binding |
A | 0070062 | cellular_component | extracellular exosome |
A | 0070324 | molecular_function | thyroid hormone binding |
B | 0005179 | molecular_function | hormone activity |
B | 0005515 | molecular_function | protein binding |
B | 0005576 | cellular_component | extracellular region |
B | 0005615 | cellular_component | extracellular space |
B | 0005737 | cellular_component | cytoplasm |
B | 0006144 | biological_process | purine nucleobase metabolic process |
B | 0007165 | biological_process | signal transduction |
B | 0035578 | cellular_component | azurophil granule lumen |
B | 0042802 | molecular_function | identical protein binding |
B | 0070062 | cellular_component | extracellular exosome |
B | 0070324 | molecular_function | thyroid hormone binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE LU2 A 201 |
Chain | Residue |
A | LYS15 |
A | HOH358 |
A | HOH438 |
A | LYS15 |
A | ALA108 |
A | LEU110 |
A | SER117 |
A | SER117 |
A | THR118 |
A | THR119 |
A | THR119 |
site_id | AC2 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE GOL A 202 |
Chain | Residue |
A | SER85 |
A | PRO86 |
A | PHE87 |
A | TYR114 |
A | HOH337 |
A | HOH389 |
B | ASN98 |
B | ARG103 |
B | HOH316 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL A 203 |
Chain | Residue |
A | ARG103 |
A | HOH317 |
A | HOH349 |
A | HOH406 |
B | HOH347 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE NA A 204 |
Chain | Residue |
A | ASP99 |
A | HOH401 |
A | HOH402 |
A | HOH403 |
A | HOH404 |
A | HOH405 |
site_id | AC5 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE LU2 B 201 |
Chain | Residue |
B | LYS15 |
B | LYS15 |
B | LEU17 |
B | ALA108 |
B | LEU110 |
B | LEU110 |
B | SER117 |
B | SER117 |
B | THR118 |
B | THR119 |
B | THR119 |
B | HOH362 |
B | HOH362 |
B | HOH413 |
site_id | AC6 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE GOL B 202 |
Chain | Residue |
A | SER117 |
A | HOH447 |
A | HOH447 |
B | LEU110 |
B | LEU111 |
B | SER112 |
B | SER115 |
B | TYR116 |
B | SER117 |
B | SER117 |
B | HOH381 |
B | HOH381 |
B | HOH382 |
Functional Information from PROSITE/UniProt
site_id | PS00768 |
Number of Residues | 16 |
Details | TRANSTHYRETIN_1 Transthyretin signature 1. KVLDavrGsPAinVaV |
Chain | Residue | Details |
A | LYS15-VAL30 | |
site_id | PS00769 |
Number of Residues | 13 |
Details | TRANSTHYRETIN_2 Transthyretin signature 2. YTIAalLSPYSYS |
Chain | Residue | Details |
A | TYR105-SER117 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | LYS15 | |
A | GLU54 | |
A | SER117 | |
B | LYS15 | |
B | GLU54 | |
B | SER117 | |
Chain | Residue | Details |
A | CYS10 | |
B | CYS10 | |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | MOD_RES: 4-carboxyglutamate; in a patient with Moyamoya disease => ECO:0000269|PubMed:18221012 |
Chain | Residue | Details |
A | GLU42 | |
B | GLU42 | |
Chain | Residue | Details |
A | SER52 | |
B | SER52 | |
Chain | Residue | Details |
A | ASN98 | |
B | ASN98 | |