4QWW
Crystal structure of the Fab410-BfAChE complex
Summary for 4QWW
Entry DOI | 10.2210/pdb4qww/pdb |
Descriptor | Acetylcholinesterase, Fab410 antibody light chain, Fab410 antibody heavy chain, ... (8 entities in total) |
Functional Keywords | a/b hydrolase fold, acetylcholinesterase, monoclonal antibody, hydrolase-immune system complex, hydrolase/immune system |
Biological source | Bungarus fasciatus (Banded krait) More |
Total number of polymer chains | 6 |
Total formula weight | 222193.03 |
Authors | Bourne, Y.,Renault, L.,Marchot, P. (deposition date: 2014-07-17, release date: 2014-11-26, Last modification date: 2023-09-20) |
Primary citation | Bourne, Y.,Renault, L.,Marchot, P. Crystal Structure of Snake Venom Acetylcholinesterase in Complex with Inhibitory Antibody Fragment Fab410 Bound at the Peripheral Site: EVIDENCE FOR OPEN AND CLOSED STATES OF A BACK DOOR CHANNEL. J.Biol.Chem., 290:1522-1535, 2015 Cited by PubMed: 25411244DOI: 10.1074/jbc.M114.603902 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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