4QWW

Crystal structure of the Fab410-BfAChE complex

4QWW の概要

• エントリーDOI: 10.2210/pdb4qww/pdb
• 分子名称: Acetylcholinesterase, Fab410 antibody light chain, Fab410 antibody heavy chain, ... (8 entities in total)
• 機能のキーワード: a/b hydrolase fold, acetylcholinesterase, monoclonal antibody, hydrolase-immune system complex, hydrolase/immune system
• 由来する生物種: Bungarus fasciatus (Banded krait); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 222193.03

構造登録者

Bourne, Y.,Renault, L.,Marchot, P. (登録日: 2014-07-17, 公開日: 2014-11-26, 最終更新日: 2023-09-20)

• 主引用文献: Bourne, Y.,Renault, L.,Marchot, P.; Crystal Structure of Snake Venom Acetylcholinesterase in Complex with Inhibitory Antibody Fragment Fab410 Bound at the Peripheral Site: EVIDENCE FOR OPEN AND CLOSED STATES OF A BACK DOOR CHANNEL.; J.Biol.Chem., 290:1522-1535, 2015; PubMed: 25411244; DOI: 10.1074/jbc.M114.603902

実験手法

X-RAY DIFFRACTION (2.7 Å)