4QUG
Caspase-3 M61A
Summary for 4QUG
Entry DOI | 10.2210/pdb4qug/pdb |
Related | 4QTX 4QU0 4QU5 4QU8 4QU9 4QUA 4QUB 4QUD 4QUE 4QUH 4QUI 4QUJ 4QUL |
Related PRD ID | PRD_000238 |
Descriptor | Caspase-3, ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | allosteric network, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P42574 |
Total number of polymer chains | 4 |
Total formula weight | 64474.08 |
Authors | Cade, C.,Swartz, P.D.,MacKenzie, S.H.,Clark, A.C. (deposition date: 2014-07-10, release date: 2014-11-05, Last modification date: 2017-11-22) |
Primary citation | Cade, C.,Swartz, P.,MacKenzie, S.H.,Clark, A.C. Modifying caspase-3 activity by altering allosteric networks. Biochemistry, 53:7582-7595, 2014 Cited by PubMed: 25343534DOI: 10.1021/bi500874k PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.917 Å) |
Structure validation
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