4QRD

Structure of Methionyl-tRNA Synthetase in complex with N-(1H-benzimidazol-2-ylmethyl)-N'-(2,4-dichlorophenyl)-6-(morpholin-4-yl)-1,3,5-triazine-2,4-diamine

4QRD の概要

• エントリーDOI: 10.2210/pdb4qrd/pdb
• 関連するPDBエントリー: 4QRE
• 分子名称: Methionyl-tRNA synthetase, MAGNESIUM ION, N-(1H-benzimidazol-2-ylmethyl)-N'-(2,4-dichlorophenyl)-6-(morpholin-4-yl)-1,3,5-triazine-2,4-diamine, ... (4 entities in total)
• 機能のキーワード: protein synthesis, aminoacyl-trna synthetase, aminoacylation, cytosol, ligase-ligase inhibitor complex, ligase/ligase inhibitor
• 由来する生物種: Staphylococcus aureus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 63612.89

構造登録者

Li, X.,Hilgers, M.T.,Stidham, M.,Brown-Driver, V.,Shaw, K.J.,Finn, J. (登録日: 2014-06-30, 公開日: 2015-07-29, 最終更新日: 2024-02-28)

• 主引用文献: Li, X.,Hilgers, M.T.,Stidham, M.,Brown-Driver, V.,Shaw, K.J.,Finn, J.; Discovery and SAR of a Novel Series of Pyrimidine Antibacterials Targeting Methionyl-tRNA Synthetase; to be published,

実験手法

X-RAY DIFFRACTION (1.97 Å)