4QR9
Crystal structure of two HMGB1 Box A domains cooperating to underwind and kink a DNA
Summary for 4QR9
Entry DOI | 10.2210/pdb4qr9/pdb |
Descriptor | High mobility group protein B1, DNA (5'-D(*AP*TP*AP*TP*CP*GP*AP*TP*AP*T)-3'), MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | hmg-box, hmgb1, box a domain, high mobility group, dna-binding, bend dna, kink dna, architectural factor, minor groove, chromatin, nucleus, dna binding protein |
Biological source | Rattus norvegicus (brown rat,rat,rats) More |
Cellular location | Nucleus: P63159 |
Total number of polymer chains | 6 |
Total formula weight | 30095.03 |
Authors | Sanchez-Giraldo, R.,Acosta-Reyes, F.J.,Malarkey, C.S.,Saperas, N.,Churchill, M.E.A.,Campos, J.L. (deposition date: 2014-06-30, release date: 2015-07-01, Last modification date: 2023-09-20) |
Primary citation | Sanchez-Giraldo, R.,Acosta-Reyes, F.J.,Malarkey, C.S.,Saperas, N.,Churchill, M.E.,Campos, J.L. Two high-mobility group box domains act together to underwind and kink DNA. Acta Crystallogr.,Sect.D, 71:1423-1432, 2015 Cited by PubMed: 26143914DOI: 10.1107/S1399004715007452 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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