4QOZ

Crystal structure of the histone mRNA stem-loop, stem-loop binding protein (phosphorylated), and 3'hExo ternary complex

4QOZ の概要

• エントリーDOI: 10.2210/pdb4qoz/pdb
• 関連するPDBエントリー: 4L8R
• 分子名称: histone mRNA stem-loop, 3'-5' exoribonuclease 1, Histone RNA hairpin-binding protein, ... (4 entities in total)
• 機能のキーワード: histone mrna 3'-end processing, histone mrna translation, microrna homeostasis, 5.8s rrna 3'-end maturation, zfp100, lsm11, phosphorylation, nucleus, rna-hydrolase-rna binding protein complex, rna/hydrolase/rna binding protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: Q8IV48 Q14493
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 101292.06

構造登録者

Tan, D.,Tong, L. (登録日: 2014-06-21, 公開日: 2014-07-23, 最終更新日: 2014-08-06)

• 主引用文献: Zhang, J.,Tan, D.,DeRose, E.F.,Perera, L.,Dominski, Z.,Marzluff, W.F.,Tong, L.,Hall, T.M.; Molecular mechanisms for the regulation of histone mRNA stem-loop-binding protein by phosphorylation.; Proc.Natl.Acad.Sci.USA, 111:E2937-E2946, 2014; PubMed: 25002523; DOI: 10.1073/pnas.1406381111

実験手法

X-RAY DIFFRACTION (2.304 Å)