4QN2

2.6 Angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betB) G234S mutant from Staphylococcus aureus (IDP00699) in complex with NAD+ and BME-free Cys289

Replaces:  4NI4

Summary for 4QN2

• Entry DOI: 10.2210/pdb4qn2/pdb
• Related: 4MPB 4MPY 4NEA 4NU9 4Q92 4QJE
• Descriptor: Betaine aldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ACETATE ION, ... (4 entities in total)
• Functional Keywords: betb, structural genomics, nad, niaid, national institute of allergy and infectious diseases, csgid, rossmann fold, center for structural genomics of infectious diseases, oxidoreductase
• Biological source: Staphylococcus aureus subsp. aureus
• Total number of polymer chains: 8
• Total formula weight: 462535.69

Authors

Halavaty, A.S.,Minasov, G.,Chen, C.,Joo, J.C.,Yakunin, A.F.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-06-17, release date: 2014-07-02, Last modification date: 2023-09-20)

• Primary citation: Halavaty, A.S.,Rich, R.L.,Chen, C.,Joo, J.C.,Minasov, G.,Dubrovska, I.,Winsor, J.R.,Myszka, D.G.,Duban, M.,Shuvalova, L.,Yakunin, A.F.,Anderson, W.F.; Structural and functional analysis of betaine aldehyde dehydrogenase from Staphylococcus aureus.; Acta Crystallogr.,Sect.D, 71:1159-1175, 2015; PubMed: 25945581; DOI: 10.1107/S1399004715004228

Experimental method

X-RAY DIFFRACTION (2.6 Å)