4QKL
Influenza A M2 wild type TM domain at high pH in the lipidic cubic phase under room temperature diffraction conditions
Summary for 4QKL
Entry DOI | 10.2210/pdb4qkl/pdb |
Related | 4QK6 4QK7 4QKC 4QKM |
Descriptor | influenza M2 monomer, TM domain (22-46), CHLORIDE ION, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | transmembrane alpha helix, ph-activated proton channel, viral protein |
Biological source | Influenza A virus |
Cellular location | Virion membrane : W8PGZ1 |
Total number of polymer chains | 1 |
Total formula weight | 2932.02 |
Authors | Thomaston, J.L.,DeGrado, W.F. (deposition date: 2014-06-06, release date: 2015-11-11, Last modification date: 2023-09-20) |
Primary citation | Thomaston, J.L.,Alfonso-Prieto, M.,Woldeyes, R.A.,Fraser, J.S.,Klein, M.L.,Fiorin, G.,DeGrado, W.F. High-resolution structures of the M2 channel from influenza A virus reveal dynamic pathways for proton stabilization and transduction. Proc.Natl.Acad.Sci.USA, 112:14260-14265, 2015 Cited by PubMed: 26578770DOI: 10.1073/pnas.1518493112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.711 Å) |
Structure validation
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