4QI9

Crystal structure of dihydrofolate reductase from Yersinia pestis complexed with methotrexate

Summary for 4QI9

• Entry DOI: 10.2210/pdb4qi9/pdb
• Related: 3Q1H
• Descriptor: Dihydrofolate reductase, METHOTREXATE (3 entities in total)
• Functional Keywords: structural genomics, center for structural genomics of infectious diseases, csgid, alpha beta fold, niaid, national institute of allergy and infectious diseases, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Yersinia pestis
• Total number of polymer chains: 3
• Total formula weight: 59139.01

Authors

Maltseva, N.,Kim, Y.,Makowska-Grzyska, M.,Mulligan, R.,Shatsman, S.,Anderson, W.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-05-30, release date: 2014-07-02, Last modification date: 2024-11-06)

• Primary citation: Maltseva, N.,Kim, Y.,Makowska-Grzyska, M.,Mulligan, R.,Shatsman, S.,Anderson, W.F.,Joachimiak, A.; Crystal structure of dihydrofolate reductase from Yersinia pestis complexed with methotrexate; To be Published,

Experimental method

X-RAY DIFFRACTION (2.297 Å)