4QI9
Crystal structure of dihydrofolate reductase from Yersinia pestis complexed with methotrexate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Dihydrofolate reductase | polymer | 167 | 19258.6 | 3 | UniProt (Q7CG83) Pfam (PF00186) UniProt (by SIFTS) (A0A3N4BLI0) | Yersinia pestis | |
| 2 | D, E, F (A, B, C) | METHOTREXATE | non-polymer | 454.4 | 3 | Chemie (MTX) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 80 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 160 (UniProt: Q7CG83)
| PDB | External Database | Details |
|---|---|---|
| Gly 161 | - | expression tag |
| Glu 162 | - | expression tag |
| Asn 163 | - | expression tag |
| Leu 164 | - | expression tag |
| Tyr 165 | - | expression tag |
| Phe 166 | - | expression tag |
| Gln 167 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 57775.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1363.3 | |
| All* | Total formula weight | 59139.0 |
