4QGN
Human acireductone dioxygenase with iron ion and L-methionine in active center
Summary for 4QGN
Entry DOI | 10.2210/pdb4qgn/pdb |
Descriptor | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, FE (III) ION, CHLORIDE ION, ... (7 entities in total) |
Functional Keywords | rmlc-like cupin, oxidoreductase, iron binding, 1, 2-dihydroxy-5-(methylthio)pent-1-en-3-one dioxygenase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9BV57 |
Total number of polymer chains | 1 |
Total formula weight | 22566.85 |
Authors | Milaczewska, A.M.,Chruszcz, M.,Petkowski, J.J.,Niedzialkowska, E.,Minor, W.,Borowski, T. (deposition date: 2014-05-23, release date: 2015-05-27, Last modification date: 2023-12-06) |
Primary citation | Milaczewska, A.,Kot, E.,Amaya, J.A.,Makris, T.M.,Zajac, M.,Korecki, J.,Chumakov, A.,Trzewik, B.,Kedracka-Krok, S.,Minor, W.,Chruszcz, M.,Borowski, T. On the Structure and Reaction Mechanism of Human Acireductone Dioxygenase. Chemistry, 24:5225-5237, 2018 Cited by PubMed: 29193386DOI: 10.1002/chem.201704617 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.05 Å) |
Structure validation
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