4QGN

Human acireductone dioxygenase with iron ion and L-methionine in active center

4QGN の概要

• エントリーDOI: 10.2210/pdb4qgn/pdb
• 分子名称: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, FE (III) ION, CHLORIDE ION, ... (7 entities in total)
• 機能のキーワード: rmlc-like cupin, oxidoreductase, iron binding, 1, 2-dihydroxy-5-(methylthio)pent-1-en-3-one dioxygenase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: Q9BV57
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 22566.85

構造登録者

Milaczewska, A.M.,Chruszcz, M.,Petkowski, J.J.,Niedzialkowska, E.,Minor, W.,Borowski, T. (登録日: 2014-05-23, 公開日: 2015-05-27, 最終更新日: 2023-12-06)

• 主引用文献: Milaczewska, A.,Kot, E.,Amaya, J.A.,Makris, T.M.,Zajac, M.,Korecki, J.,Chumakov, A.,Trzewik, B.,Kedracka-Krok, S.,Minor, W.,Chruszcz, M.,Borowski, T.; On the Structure and Reaction Mechanism of Human Acireductone Dioxygenase.; Chemistry, 24:5225-5237, 2018; PubMed: 29193386; DOI: 10.1002/chem.201704617

実験手法

X-RAY DIFFRACTION (3.05 Å)