4QEI

Two distinct conformational states of GlyRS captured in crystal lattice

4QEI の概要

• エントリーDOI: 10.2210/pdb4qei/pdb
• 分子名称: Glycine--tRNA ligase, tRNA-Gly-CCC-2-2, ADENOSINE MONOPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: aminoacyl-trna synthetase, glycylation, glycyl-trna synthetase, trna ligase, ligase-rna complex, ligase/rna
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm : P41250
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 94430.99

構造登録者

Xie, W.,Qin, X.,Deng, X.,Zhang, Q.,Li, Q. (登録日: 2014-05-16, 公開日: 2015-05-20, 最終更新日: 2023-11-08)

• 主引用文献: Deng, X.,Qin, X.,Chen, L.,Jia, Q.,Zhang, Y.,Zhang, Z.,Lei, D.,Ren, G.,Zhou, Z.,Wang, Z.,Li, Q.,Xie, W.; Large Conformational Changes of Insertion 3 in Human Glycyl-tRNA Synthetase (hGlyRS) during Catalysis; J.Biol.Chem., 291:5740-5752, 2016; PubMed: 26797133; DOI: 10.1074/jbc.M115.679126

実験手法

X-RAY DIFFRACTION (2.875 Å)