4QBV
Crystal structure of C117T mutant of human acidic fibroblast growth factor in sodium citrate buffer
Summary for 4QBV
Entry DOI | 10.2210/pdb4qbv/pdb |
Related | 1JQZ 1JY0 1RG8 2AFG 3FJE 3FJF 3FJH 3FJK 4Q91 4Q9G 4Q9P 4QAL 4QBC |
Descriptor | Fibroblast growth factor 1, CITRATE ANION (3 entities in total) |
Functional Keywords | beta-trefoil, growth factor, fgfr binding, heparin binding, protein binding |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P05230 |
Total number of polymer chains | 2 |
Total formula weight | 33747.62 |
Authors | Blaber, M.,Xia, X. (deposition date: 2014-05-08, release date: 2015-03-11, Last modification date: 2024-02-28) |
Primary citation | Xia, X.,Longo, L.M.,Blaber, M. Mutation choice to eliminate buried free cysteines in protein therapeutics. J.Pharm.Sci., 104:566-576, 2015 Cited by PubMed: 25312595DOI: 10.1002/jps.24188 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.497 Å) |
Structure validation
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