4QBV

Crystal structure of C117T mutant of human acidic fibroblast growth factor in sodium citrate buffer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Fibroblast growth factor 1	polymer	146	16684.7	2	UniProt (P05230) Pfam (PF00167) In PDB	Homo sapiens (human)	FGF-1, Acidic fibroblast growth factor, aFGF, Endothelial cell growth factor, ECGF, Heparin-binding growth factor 1, HBGF-1
2	A, B	CITRATE ANION	non-polymer		189.1	2	Chemie (FLC)
3		water	water		18.0	413	Chemie (HOH)

Sequence modifications

A, B: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Thr 117	Cys 132	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33369.4
Non-Polymers*	Number of molecules	2
	Total formula weight	378.2
All*	Total formula weight	33747.6

*Water molecules are not included.