4Q9I
P-glycoprotein cocrystallised with QZ-Ala
Summary for 4Q9I
Entry DOI | 10.2210/pdb4q9i/pdb |
Related | 4Q9H 4Q9J 4Q9K 4Q9L |
Related PRD ID | PRD_001236 |
Descriptor | Multidrug resistance protein 1A, (30F)A(30F)A(30F)A Peptide (2 entities in total) |
Functional Keywords | membrane protein, transporter, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Mus musculus (mouse) |
Cellular location | Cell membrane; Multi-pass membrane protein: P21447 |
Total number of polymer chains | 3 |
Total formula weight | 143270.58 |
Authors | McGrath, A.P.,Szewczyk, P.,Chang, G. (deposition date: 2014-05-01, release date: 2015-03-04, Last modification date: 2024-07-10) |
Primary citation | Szewczyk, P.,Tao, H.,McGrath, A.P.,Villaluz, M.,Rees, S.D.,Lee, S.C.,Doshi, R.,Urbatsch, I.L.,Zhang, Q.,Chang, G. Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein. Acta Crystallogr.,Sect.D, 71:732-741, 2015 Cited by PubMed: 25760620DOI: 10.1107/S1399004715000978 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.781 Å) |
Structure validation
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