4Q8Q
tRNA-Guanine Transglycosylase (TGT) Mutant V262C in Complex with 6-Amino-2-{[2-(morpholin-4-yl)ethyl]amino}-1H,7H,8H-imidazo[4,5-g]quinazolin-8-one
Summary for 4Q8Q
Entry DOI | 10.2210/pdb4q8q/pdb |
Related | 1PUD 4Q8M 4Q8N 4Q8O 4Q8P |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, 6-amino-2-[(2-morpholin-4-ylethyl)amino]-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, ... (4 entities in total) |
Functional Keywords | transferase, preq1, trna, guanine exchange enzyme, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Zymomonas mobilis subsp. mobilis |
Total number of polymer chains | 1 |
Total formula weight | 43468.61 |
Authors | |
Primary citation | Neeb, M.,Heine, A.,Klebe, G. Creating a Resistance Model for TGT: The Effect of Mutations on Flexible lin-Benzoguanine Substituents To be Published, |
Experimental method | X-RAY DIFFRACTION (1.721 Å) |
Structure validation
Download full validation report