4Q8Q

tRNA-Guanine Transglycosylase (TGT) Mutant V262C in Complex with 6-Amino-2-{[2-(morpholin-4-yl)ethyl]amino}-1H,7H,8H-imidazo[4,5-g]quinazolin-8-one

4Q8Q の概要

• エントリーDOI: 10.2210/pdb4q8q/pdb
• 関連するPDBエントリー: 1PUD 4Q8M 4Q8N 4Q8O 4Q8P
• 分子名称: Queuine tRNA-ribosyltransferase, ZINC ION, 6-amino-2-[(2-morpholin-4-ylethyl)amino]-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, ... (4 entities in total)
• 機能のキーワード: transferase, preq1, trna, guanine exchange enzyme, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Zymomonas mobilis subsp. mobilis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43468.61

構造登録者

Neeb, M.,Heine, A.,Klebe, G. (登録日: 2014-04-28, 公開日: 2015-05-20, 最終更新日: 2023-09-20)

• 主引用文献: Neeb, M.,Heine, A.,Klebe, G.; Creating a Resistance Model for TGT: The Effect of Mutations on Flexible lin-Benzoguanine Substituents; To be Published,

実験手法

X-RAY DIFFRACTION (1.721 Å)