4Q8P
tRNA-Guanine Transglycosylase (TGT) Mutant V262D in Complex with 6-Amino-2-{[2-(morpholin-4-yl)ethyl]amino}-1H,7H,8H-imidazo[4,5-g]quinazolin-8-one
Summary for 4Q8P
Entry DOI | 10.2210/pdb4q8p/pdb |
Related | 1PUD 4Q8M 4Q8N 4Q8O 4Q8Q |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | guanine exchange enzyme, preq1, trna, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Zymomonas mobilis subsp. mobilis |
Total number of polymer chains | 1 |
Total formula weight | 43756.83 |
Authors | |
Primary citation | Neeb, M.,Heine, A.,Klebe, G. Creating a Resistance Model for TGT: The Effect of Mutations on Flexible lin-Benzoguanine Substituents To be Published, |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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