4Q6G

Crystal Structure of the C-terminal domain of AcKRS-1 bound with N-acetyl-lysine and ADPNP

Summary for 4Q6G

Entry DOI	10.2210/pdb4q6g/pdb
Descriptor	Pyrrolysine--tRNA ligase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	trna synthetase, trna, amino acids, ligase
Biological source	Methanosarcina mazei
Cellular location	Cytoplasm : Q8PWY1
Total number of polymer chains	1
Total formula weight	31879.07
Authors	Eiler, D.R.,Kavran, J.,Steitz, T.A. (deposition date: 2014-04-22, release date: 2014-11-12, Last modification date: 2023-12-06)
Primary citation	Guo, L.T.,Wang, Y.S.,Nakamura, A.,Eiler, D.,Kavran, J.M.,Wong, M.,Kiessling, L.L.,Steitz, T.A.,O'Donoghue, P.,Soll, D. Polyspecific pyrrolysyl-tRNA synthetases from directed evolution. Proc.Natl.Acad.Sci.USA, 111:16724-16729, 2014 Cited by PubMed: 25385624 DOI: 10.1073/pnas.1419737111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation