4Q5E

Shigella Effector Kinase OspG bound to E2-Ub UbcH7-Ub Conjugate

4Q5E の概要

• エントリーDOI: 10.2210/pdb4q5e/pdb
• 関連するPDBエントリー: 4Q5H
• 分子名称: Protein kinase OspG, Polyubiquitin, Ubiquitin-conjugating enzyme E2 L3, ... (4 entities in total)
• 機能のキーワード: protein-protein complex, structural genomics, montreal-kingston bacterial structural genomics initiative, bsgi, kinase fold, inhibition of nf-kb pathway, unknown function, protein binding
• 由来する生物種: Shigella sonnei Ss046; 詳細
• 細胞内の位置: Secreted : Q3YTH2; Cytoplasm : P0CG63; Nucleus : P68036
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 46812.08

構造登録者

Cygler, M.,Grishin, A.M.,Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) (登録日: 2014-04-16, 公開日: 2014-07-02, 最終更新日: 2017-11-22)

• 主引用文献: Grishin, A.M.,Condos, T.E.,Barber, K.R.,Campbell-Valois, F.X.,Parsot, C.,Shaw, G.S.,Cygler, M.; Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG.; Structure, 22:878-888, 2014; PubMed: 24856362; DOI: 10.1016/j.str.2014.04.010

実験手法

X-RAY DIFFRACTION (1.869 Å)