4Q2Z

Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE356, from a non-human primate

Summary for 4Q2Z

Related4KTD 4KTE
DescriptorHeavy chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, Light chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody (3 entities in total)
Functional Keywordsfab fragment, hiv viral envelope glycoprotein neutralization, immune system
Biological sourceMacaca mulatta
Total number of polymer chains4
Total molecular weight95830.75
Authors
Primary citation
Navis, M.,Tran, K.,Bale, S.,Phad, G.E.,Guenaga, J.,Wilson, R.,Soldemo, M.,McKee, K.,Sundling, C.,Mascola, J.,Li, Y.,Wyatt, R.T.,Karlsson Hedestam, G.B.
HIV-1 Receptor Binding Site-Directed Antibodies Using a VH1-2 Gene Segment Orthologue Are Activated by Env Trimer Immunization.
Plos Pathog., 10:e1004337-e1004337, 2014
PubMed: 25166308 (PDB entries with the same primary citation)
DOI: 10.1371/journal.ppat.1004337
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.93 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27371.2%6.4%6.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4q2z
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Molmil generated image of 4q2z
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Molmil generated image of 4q2z
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 4q2z
no rotation
Molmil generated image of 4q2z
rotated about x axis by 90°
Molmil generated image of 4q2z
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (4q2z.pdb2.gz [138.76 KB])
Coordinate files for Biological unit (4q2z.pdb1.gz [137.83 KB])