4Q1S
Yeast 20S proteasome in Complex with Kendomycin
Summary for 4Q1S
Entry DOI | 10.2210/pdb4q1s/pdb |
Related | 1RYP |
Descriptor | Proteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-5, ... (16 entities in total) |
Functional Keywords | proteasome, natural product, quinone methide, covalent binding, exosite, hydrolase-toxin complex, hydrolase/toxin |
Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
Cellular location | Cytoplasm: P23639 P22141 P30656 P23724 P30657 P38624 P23638 P40303 P32379 P40302 P21242 P21243 P25043 P25451 |
Total number of polymer chains | 28 |
Total formula weight | 732028.08 |
Authors | Beck, P.,Heinemeyer, W.,Spaeth, A.,Elnakady, Y.,Mueller, R.,Groll, M. (deposition date: 2014-04-04, release date: 2014-07-30, Last modification date: 2023-09-20) |
Primary citation | Beck, P.,Heinemeyer, W.,Spath, A.L.,Elnakady, Y.,Muller, R.,Groll, M. Interactions of the natural product kendomycin and the 20S proteasome. J.Mol.Biol., 426:3108-3117, 2014 Cited by PubMed: 25038530DOI: 10.1016/j.jmb.2014.06.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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