4PY8
Crystal structure of Fab 3.1 in complex with the 1918 influenza virus hemagglutinin
Summary for 4PY8
Entry DOI | 10.2210/pdb4py8/pdb |
Related | 4PY7 |
Descriptor | Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, antibody 3.1 heavy chain, ... (7 entities in total) |
Functional Keywords | hemagglutinin glycoproteins, immunoglobulin fab fragment, membrane fusion, neutralizing antibodies, viral protein-immune system complex, viral protein/immune system |
Biological source | Influenza A virus More |
Cellular location | Virion membrane; Single-pass type I membrane protein (Potential): Q9WFX3 Q9WFX3 |
Total number of polymer chains | 4 |
Total formula weight | 104681.52 |
Authors | Dreyfus, C. (deposition date: 2014-03-26, release date: 2014-05-21, Last modification date: 2020-07-29) |
Primary citation | Wyrzucki, A.,Dreyfus, C.,Kohler, I.,Steck, M.,Wilson, I.A.,Hangartner, L. Alternative Recognition of the Conserved Stem Epitope in Influenza A Virus Hemagglutinin by a VH3-30-Encoded Heterosubtypic Antibody. J.Virol., 88:7083-7092, 2014 Cited by PubMed: 24719426DOI: 10.1128/JVI.00178-14 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.91 Å) |
Structure validation
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